CIPLA LTD. (INDIA)
Pirfenidone: It contains the Drug / Molecule “Pirfenidone”. Pirefenex exhibits both anti-inflammatory and antifibrotic effects. Much attention has been focused the antifibrotic effect of the drug. pirfenidone reduces fibroblast proliferation inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.Pirfenidone has also been shown to reduce production of inflammatory mediators such as TNF-α and IL-1β in both cultured cells and isolated human peripheral blood
Pirfenex has used to treat mild to moderate forms of a certain lung disease calledidiopathic pulmonary fibrosis (IPF).